Phosphoserine phosphatase (PSPH) (NM_004577) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human phosphoserine phosphatase (PSPH)
Synonyms
PSP; PSPHD
Gene ID
5723
UniProt
P78330, A0A024RDL3
Accession Number mRNA
NM_004577
Chromosomal Location
7p11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Glycine, serine and threonine metabolism, Metabolic pathways
Field of Research
Glycine, serine and threonine metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Phosphatase
Molecular Weight
24.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PSPH
Species
Human
Protein ID
NP_004568
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5723
Uniprot URL
https://www.uniprot.org/uniprot/P78330
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004577
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004568
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