SSPN (NM_005086) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the dystrophin-glycoprotein complex (DGC) . The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Two alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]

Overview

Recombinant protein of human sarcospan (Kras oncogene-associated gene) (SSPN), transcript variant 1

Synonyms

DAGA5; KRAG; NSPN; SPN1; SPN2

Gene ID

8082

UniProt

Q14714

Accession Number mRNA

NM_005086

Chromosomal Location

12p12.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

26.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.