STX1B (NM_052874) Human Recombinant Protein
Selected Variant
PH37793M5
Size: 20 µg
Product Specifications
Background
The protein encoded by this gene belongs to a family of proteins thought to play a role in the exocytosis of synaptic vesicles. Vesicle exocytosis releases vesicular contents and is important to various cellular functions. For instance, the secretion of transmitters from neurons plays an important role in synaptic transmission. After exocytosis, the membrane and proteins from the vesicle are retrieved from the plasma membrane through the process of endocytosis. Mutations in this gene have been identified as one cause of fever-associated epilepsy syndromes. A possible link between this gene and Parkinson's disease has also been suggested. [provided by RefSeq, Jan 2015]
Overview
Recombinant protein of human syntaxin 1B (STX1B)
Synonyms
GEFSP9; STX1B1; STX1B2
Gene ID
112755
UniProt
P61266
Accession Number mRNA
NM_052874
Chromosomal Location
16p11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
SNARE interactions in vesicular transport
Field of Research
SNARE interactions in vesicular transport
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
33.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
STX1B
Species
Human
Protein ID
NP_443106
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/112755
Uniprot URL
https://www.uniprot.org/uniprot/P61266
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_052874
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_443106
Price
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