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STX1B (NM_052874) Human Recombinant Protein

Selected Variant

PH37793M5

Size: 20 µg

Product Specifications

Background

The protein encoded by this gene belongs to a family of proteins thought to play a role in the exocytosis of synaptic vesicles. Vesicle exocytosis releases vesicular contents and is important to various cellular functions. For instance, the secretion of transmitters from neurons plays an important role in synaptic transmission. After exocytosis, the membrane and proteins from the vesicle are retrieved from the plasma membrane through the process of endocytosis. Mutations in this gene have been identified as one cause of fever-associated epilepsy syndromes. A possible link between this gene and Parkinson's disease has also been suggested. [provided by RefSeq, Jan 2015]

Overview

Recombinant protein of human syntaxin 1B (STX1B)

Synonyms

GEFSP9; STX1B1; STX1B2

Gene ID

112755

UniProt

P61266

Accession Number mRNA

NM_052874

Chromosomal Location

16p11.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

SNARE interactions in vesicular transport

Field of Research

SNARE interactions in vesicular transport

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

33.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

STX1B

Species

Human

Protein ID

NP_443106

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/112755

Uniprot URL

https://www.uniprot.org/uniprot/P61266

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_052874

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_443106

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