ANKRD16 (NM_019046) Human Recombinant Protein
Product Specifications
Background
Required to prevent the misactivation of serine (Ser) with tRNA (Ala) by promoting the hydrolysis of Ser-mischarged tRNA (Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA (Ala) and precluding Ser misincorporation in nascent peptides.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human ankyrin repeat domain 16 (ANKRD16), transcript variant 1
Synonyms
Ankyrin repeat domain 16; OTTHUMP00000019019; OTTHUMP00000044872
Gene ID
54522
UniProt
Q6P6B7
Accession Number mRNA
NM_019046
Chromosomal Location
10p15.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
39.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ANKRD16
Species
Human
Protein ID
NP_061919
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54522
Uniprot URL
https://www.uniprot.org/uniprot/Q6P6B7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019046
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_061919
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