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ANKRD16 (NM_019046) Human Recombinant Protein

Product Specifications

Background

Required to prevent the misactivation of serine (Ser) with tRNA (Ala) by promoting the hydrolysis of Ser-mischarged tRNA (Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA (Ala) and precluding Ser misincorporation in nascent peptides.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human ankyrin repeat domain 16 (ANKRD16), transcript variant 1

Synonyms

Ankyrin repeat domain 16; OTTHUMP00000019019; OTTHUMP00000044872

Gene ID

54522

UniProt

Q6P6B7

Accession Number mRNA

NM_019046

Chromosomal Location

10p15.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

39.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ANKRD16

Species

Human

Protein ID

NP_061919

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/54522

Uniprot URL

https://www.uniprot.org/uniprot/Q6P6B7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_019046

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_061919

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