ASAP3 (NM_017707) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of a subfamily of ADP-ribosylation factor (Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

Overview

Recombinant protein of human ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 (ASAP3), transcript variant 1

Synonyms

ACAP4; CENTB6; DDEFL1; UPLC1

Gene ID

55616

UniProt

Q8TDY4, A0A024RAB1

Accession Number mRNA

NM_017707

Chromosomal Location

1p36.12

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Endocytosis, Fc gamma R-mediated phagocytosis

Field of Research

Endocytosis, Fc gamma R-mediated phagocytosis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

99 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.