GNAQ (NM_002072) Human Recombinant Protein
Selected Variant
PH37764M5
Size: 20 µg
Product Specifications
Background
This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010]
Overview
Recombinant protein of human guanine nucleotide binding protein (G protein), q polypeptide (GNAQ)
Synonyms
CMC1; G-ALPHA-q; GAQ; SWS
Gene ID
2776
UniProt
P50148, A0A024R240
Accession Number mRNA
NM_002072
Chromosomal Location
9q21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Alzheimer's disease, Calcium signaling pathway, Gap junction, GnRH signaling pathway, Huntington's disease, Long-term depression, Long-term potentiation, Melanogenesis, Vascular smooth muscle contraction
Field of Research
Alzheimer's disease, Calcium signaling pathway, Gap junction, GnRH signaling pathway, Huntington's disease, Long-term depression, Long-term potentiation, Melanogenesis, Vascular smooth muscle contraction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
42 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GNAQ
Species
Human
Protein ID
NP_002063
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2776
Uniprot URL
https://www.uniprot.org/uniprot/P50148
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002072
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002063
Price
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