HS3ST1 (NM_005114) Human Recombinant Protein
Product Specifications
Background
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It possesses both heparan sulfate glucosaminyl 3-O-sulfotransferase activity, anticoagulant heparan sulfate conversion activity, and is a rate limiting enzyme for synthesis of anticoagulant heparan. This enzyme is an intraluminal Golgi resident protein. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (HS3ST1)
Synonyms
3OST; 3OST1
Gene ID
9957
UniProt
O14792, A0A024R9R4
Accession Number mRNA
NM_005114
Chromosomal Location
4p15.33
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Heparan sulfate biosynthesis
Field of Research
Heparan sulfate biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
33.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HS3ST1
Species
Human
Protein ID
NP_005105
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9957
Uniprot URL
https://www.uniprot.org/uniprot/O14792
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005114
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005105
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