IGFBP1 (NM_000596) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP N-terminal domain and a thyroglobulin type-I domain. The encoded protein, mainly expressed in the liver, circulates in the plasma and binds both insulin-like growth factors (IGFs) I and II, prolonging their half-lives and altering their interaction with cell surface receptors. This protein is important in cell migration and metabolism. Low levels of this protein may be associated with impaired glucose tolerance, vascular disease and hypertension in human patients. [provided by RefSeq, Aug 2017]
Synonyms
AFBP; hIGFBP-1; IBP1; IGF-BP25; PP12
Gene ID
3484
UniProt
P08833
Accession Number mRNA
NM_000596
Chromosomal Location
7p12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein
Molecular Weight
25.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IGFBP1
Species
Human
Protein ID
NP_000587
Overview
Recombinant protein of human insulin-like growth factor binding protein 1 (IGFBP1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3484
Uniprot URL
https://www.uniprot.org/uniprot/P08833
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000596
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000587
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