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LCN1 (NM_002297) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. The encoded protein is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9. [provided by RefSeq, Nov 2011]

Overview

Recombinant protein of human lipocalin 1 (tear prealbumin) (LCN1)

Synonyms

PMFA; TLC; TP; VEGP

Gene ID

3933

UniProt

P31025, A0A024R8D7

Accession Number mRNA

NM_002297

Chromosomal Location

9q34.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

17.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

LCN1

Species

Human

Protein ID

NP_002288

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3933

Uniprot URL

https://www.uniprot.org/uniprot/P31025

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002297

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002288

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