THEM4 (NM_053055) Human Recombinant Protein
Selected Variant
PH37679M5
Size: 20 µg
Product Specifications
Background
Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human thioesterase superfamily member 4 (THEM4)
Synonyms
CTMP
Gene ID
117145
UniProt
Q5T1C6, A8K0C9
Accession Number mRNA
NM_053055
Chromosomal Location
1q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
26.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
THEM4
Species
Human
Protein ID
NP_444283
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/117145
Uniprot URL
https://www.uniprot.org/uniprot/Q5T1C6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_053055
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_444283
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