TCTN1 (NM_001082537) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Synonyms
JBTS13; TECT1
Gene ID
79600
UniProt
Q2MV58, B4DIB9
Accession Number mRNA
NM_001082537
Chromosomal Location
12q24.11
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
63.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TCTN1
Species
Human
Protein ID
NP_001076006
Overview
Recombinant protein of human tectonic family member 1 (TCTN1), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79600
Uniprot URL
https://www.uniprot.org/uniprot/Q2MV58
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001082537
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001076006
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