HRPT2 (CDC73) (NM_024529) Human Recombinant Protein
Product Specifications
Background
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]
Overview
Recombinant protein of human cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) (CDC73)
Synonyms
C1orf28; FIHP; HPTJT; HRPT1; HRPT2; HYX
Gene ID
79577
UniProt
Q6P1J9
Accession Number mRNA
NM_024529
Chromosomal Location
1q31.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
60.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CDC73
Species
Human
Protein ID
NP_078805
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79577
Uniprot URL
https://www.uniprot.org/uniprot/Q6P1J9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024529
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_078805
Curated Selection
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