KLHL13 (NM_033495) Human Recombinant Protein
Product Specifications
Background
This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Synonyms
BKLHD2
Gene ID
90293
UniProt
Q9P2N7, Q96HC9
Accession Number mRNA
NM_033495
Chromosomal Location
Xq24
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
73.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KLHL13
Species
Human
Protein ID
NP_277030
Overview
Recombinant protein of human kelch-like 13 (Drosophila) (KLHL13)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/90293
Uniprot URL
https://www.uniprot.org/uniprot/Q9P2N7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_033495
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_277030
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