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LLGL2 (NM_001031803) Human Recombinant Protein

Selected Variant

PH37599M5

Size: 20 µg

Product Specifications

Background

The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC) . In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Homo sapiens lethal giant larvae homolog 2 (Drosophila) (LLGL2), transcript variant 3

Synonyms

HGL; Hugl-2; LGL2

Gene ID

3993

UniProt

Q6P1M3, A0PJJ0

Accession Number mRNA

NM_001031803

Chromosomal Location

17q25.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Tight junction

Field of Research

Tight junction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

113.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

LLGL2

Species

Human

Protein ID

NP_001026973

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3993

Uniprot URL

https://www.uniprot.org/uniprot/Q6P1M3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001031803

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001026973

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