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PRMT10 (PRMT9) (NM_138364) Human Recombinant Protein

Product Specifications

Background

This gene encodes a type II methyltransferase. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to the guanidino nitrogen atoms of arginine. The protein encoded by this gene methylates spliceosome associated protein 145 to regulate alternative splicing and acts as a modulator of small nuclear ribonucleoprotein maturation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2017]

Synonyms

PRMT10

Gene ID

90826

UniProt

Q6P2P2

Accession Number mRNA

NM_138364

Chromosomal Location

4q31.23

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

94.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PRMT9

Species

Human

Protein ID

NP_612373

Overview

Recombinant protein of human hypothetical protein BC004337 (LOC90826)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/90826

Uniprot URL

https://www.uniprot.org/uniprot/Q6P2P2

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_138364

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_612373

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