HA1 (ARHGAP45) (NM_012292) Human Recombinant Protein
Product Specifications
Background
Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human histocompatibility (minor) HA-1 (HMHA1)
Synonyms
HA-1; HLA-HA1; HMHA1
Gene ID
23526
UniProt
Q92619
Accession Number mRNA
NM_012292
Chromosomal Location
19p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
124.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ARHGAP45
Species
Human
Protein ID
NP_036424
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23526
Uniprot URL
https://www.uniprot.org/uniprot/Q92619
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012292
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036424
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