FBXO42 (NM_018994) Human Recombinant Protein
Product Specifications
Background
Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM, Dec 2010]
Synonyms
Fbx42; JFK
Gene ID
54455
UniProt
Q6P3S6
Accession Number mRNA
NM_018994
Chromosomal Location
1p36.13
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
77.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FBXO42
Species
Human
Protein ID
NP_061867
Overview
Recombinant protein of human F-box protein 42 (FBXO42)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54455
Uniprot URL
https://www.uniprot.org/uniprot/Q6P3S6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018994
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_061867
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