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SEPTIN6 (NM_145799) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]

Synonyms

SEP2; SEPT2; SEPT6

Gene ID

23157

UniProt

Q14141, Q541S4

Accession Number mRNA

NM_145799

Chromosomal Location

Xq24

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

48.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SEPTIN6

Species

Human

Protein ID

NP_665798

Overview

Recombinant protein of human septin 6 (SEPT6), transcript variant I

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/23157

Uniprot URL

https://www.uniprot.org/uniprot/Q14141

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_145799

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_665798

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