HDAC6 (NM_006044) Human Recombinant Protein
Selected Variant
PH37558M5
Size: 20 µg
Product Specifications
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human histone deacetylase 6 (HDAC6)
Synonyms
CPBHM; HD6; JM21; PPP1R90
Gene ID
10013
UniProt
Q9UBN7, A0A024QZ26, Q9NSW6
Accession Number mRNA
NM_006044
Chromosomal Location
Xp11.23
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
131.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HDAC6
Species
Human
Protein ID
NP_006035
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10013
Uniprot URL
https://www.uniprot.org/uniprot/Q9UBN7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006044
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006035
Price
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