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EEF1A1 (NM_001402) Human Recombinant Protein

Product Specifications

Background

This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human eukaryotic translation elongation factor 1 alpha 1 (EEF1A1)

Synonyms

CCS-3; CCS3; EE1A1; EEF-1; EEF1A; eEF1A-1; EF-Tu; EF1A; GRAF-1EF; HNGC:16303; LENG7; PTI1

Gene ID

1915

UniProt

P68104, Q6IPS9

Accession Number mRNA

NM_001402

Chromosomal Location

6q13

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Activity

266165902662428629588400

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

50 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EEF1A1

Species

Human

Protein ID

NP_001393

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1915

Uniprot URL

https://www.uniprot.org/uniprot/P68104

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001402

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001393

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