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RFX2 (NM_000635) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human regulatory factor X, 2 (influences HLA class II expression) (RFX2), transcript variant 1

Synonyms

FLJ14226

Gene ID

5990

UniProt

P48378

Accession Number mRNA

NM_000635

Chromosomal Location

19p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transcription Factors

Molecular Weight

79.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RFX2

Species

Human

Protein ID

NP_000626

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5990

Uniprot URL

https://www.uniprot.org/uniprot/P48378

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000635

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000626

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