WEE1 (NM_003390) Human Recombinant Protein

Product Specifications

Background

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human WEE1 homolog (S. pombe) (WEE1), transcript variant 1

Synonyms

WEE1A; WEE1hu

Gene ID

7465

UniProt

P30291, Q86V29

Accession Number mRNA

NM_003390

Chromosomal Location

11p15.4

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cell cycle

Field of Research

Cell cycle

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase, Stem cell - Pluripotency

Molecular Weight

71.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.