WEE1 (NM_003390) Human Recombinant Protein
Product Specifications
Background
This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008]
Synonyms
WEE1A; WEE1hu
Gene ID
7465
UniProt
P30291, Q86V29
Accession Number mRNA
NM_003390
Chromosomal Location
11p15.4
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cell cycle
Field of Research
Cell cycle
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase, Stem cell - Pluripotency
Molecular Weight
71.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
WEE1
Species
Human
Protein ID
NP_003381
Overview
Recombinant protein of human WEE1 homolog (S. pombe) (WEE1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7465
Uniprot URL
https://www.uniprot.org/uniprot/P30291
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003390
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003381
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