VCAM1 (NM_001078) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
Overview
Recombinant protein of human vascular cell adhesion molecule 1 (VCAM1), transcript variant 1
Synonyms
CD106; INCAM-100
Gene ID
7412
UniProt
P19320
Accession Number mRNA
NM_001078
Chromosomal Location
1p21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cell adhesion molecules (CAMs), Leukocyte transendothelial migration
Field of Research
Cell adhesion molecules (CAMs), Leukocyte transendothelial migration
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Molecular Weight
78.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
VCAM1
Species
Human
Protein ID
NP_001069
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7412
Uniprot URL
https://www.uniprot.org/uniprot/P19320
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001078
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001069
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