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CRBN (NM_016302) Human Recombinant Protein

Selected Variant

PH37503M5

Size: 20 µg

Product Specifications

Background

This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Overview

Purified recombinant protein of Human cereblon (CRBN), transcript variant 1, full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

MRT2; MRT2A

Gene ID

51185

UniProt

Q96SW2

Accession Number mRNA

NM_016302

Chromosomal Location

3p26.2

Expression System

HEK293T

Tag

Myc-DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris-HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Protease

Molecular Weight

50.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CRBN

Species

Human

Protein ID

NP_057386

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/51185

Uniprot URL

https://www.uniprot.org/uniprot/Q96SW2

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_016302

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_057386

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