CRBN (NM_016302) Human Recombinant Protein
Selected Variant
PH37503M5
Size: 20 µg
Product Specifications
Background
This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Overview
Purified recombinant protein of Human cereblon (CRBN), transcript variant 1, full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
MRT2; MRT2A
Gene ID
51185
UniProt
Q96SW2
Accession Number mRNA
NM_016302
Chromosomal Location
3p26.2
Expression System
HEK293T
Tag
Myc-DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris-HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Protease
Molecular Weight
50.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CRBN
Species
Human
Protein ID
NP_057386
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51185
Uniprot URL
https://www.uniprot.org/uniprot/Q96SW2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016302
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057386
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