DNA Polymerase lambda (POLL) (NM_013274) Human Recombinant Protein
Product Specifications
Background
This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2010]
Overview
Recombinant protein of human polymerase (DNA directed), lambda (POLL)
Synonyms
BETAN; POLKAPPA
Gene ID
27343
UniProt
Q9UGP5
Accession Number mRNA
NM_013274
Chromosomal Location
10q24.32
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Base excision repair, Non-homologous end-joining
Field of Research
Base excision repair, Non-homologous end-joining
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
63.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
POLL
Species
Human
Protein ID
NP_037406
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27343
Uniprot URL
https://www.uniprot.org/uniprot/Q9UGP5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013274
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_037406
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