MSC (NM_005098) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human musculin (activated B-cell factor-1) (MSC)
Synonyms
ABF-1; ABF1; bHLHa22; MYOR
Gene ID
9242
UniProt
O60682
Accession Number mRNA
NM_005098
Chromosomal Location
8q13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
21.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MSC
Species
Human
Protein ID
NP_005089
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9242
Uniprot URL
https://www.uniprot.org/uniprot/O60682
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005098
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005089
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