Ferritin Heavy Chain (FTH1) (NM_002032) Human Recombinant Protein
Product Specifications
Background
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Synonyms
FHC; FTH; FTHL6; HFE5; PIG15; PLIF
Gene ID
2495
UniProt
P02794, A0A024R525
Accession Number mRNA
NM_002032
Chromosomal Location
11q12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Porphyrin and chlorophyll metabolism
Field of Research
Porphyrin and chlorophyll metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
21 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FTH1
Species
Human
Protein ID
NP_002023
Overview
Recombinant protein of human ferritin, heavy polypeptide 1 (FTH1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2495
Uniprot URL
https://www.uniprot.org/uniprot/P02794
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002032
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002023
Curated Selection
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