CCL3 (NM_002983) Human Recombinant Protein

Product Specifications

Background

This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]

Overview

Recombinant protein of human chemokine (C-C motif) ligand 3 (CCL3)

Synonyms

G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3

Gene ID

6348

UniProt

P10147, A0N0R1

Accession Number mRNA

NM_002983

Chromosomal Location

17q12

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway

Field of Research

Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein

Molecular Weight

9.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.