TSC22D3 (NM_004089) Human Recombinant Protein

Product Specifications

Background

This gene encodes the anti-inflammatory protein glucocorticoid (GC) -induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κ B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Overview

Recombinant protein of human TSC22 domain family, member 3 (TSC22D3), transcript variant 2

Synonyms

DIP; DSIPI; GILZ; TSC-22R

Gene ID

1831

UniProt

Q99576

Accession Number mRNA

NM_004089

Chromosomal Location

Xq22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

14.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.