ABH2 (ALKBH2) (NM_001001655) Human Recombinant Protein
Product Specifications
Background
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]) .[supplied by OMIM, Mar 2008]
Synonyms
ABH2
Gene ID
121642
UniProt
Q6NS38
Accession Number mRNA
NM_001001655
Chromosomal Location
12q24.11
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
29.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ALKBH2
Species
Human
Protein ID
NP_001001655
Overview
Recombinant protein of human alkB, alkylation repair homolog 2 (E. coli) (ALKBH2), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/121642
Uniprot URL
https://www.uniprot.org/uniprot/Q6NS38
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001001655
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001001655
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