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IFNA21 (NM_002175) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus. [provided by RefSeq, Sep 2011]

Overview

Recombinant protein of human interferon, alpha 21 (IFNA21)

Synonyms

IFN-alphaI; leIF-F; LeIF F

Gene ID

3452

UniProt

P01568

Accession Number mRNA

NM_002175

Chromosomal Location

9p21.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Antigen processing and presentation, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Regulation of autophagy, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

Field of Research

Antigen processing and presentation, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Regulation of autophagy, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein

Molecular Weight

21.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

IFNA21

Species

Human

Protein ID

NP_002166

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3452

Uniprot URL

https://www.uniprot.org/uniprot/P01568

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002175

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002166

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