KCNJ5 (NM_000890) Human Recombinant Protein
Product Specifications
Background
This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas. [provided by RefSeq, Aug 2017]
Synonyms
CIR; GIRK4; KATP1; KIR3.4; LQT13
Gene ID
3762
UniProt
P48544, A0A5J6E2W8
Accession Number mRNA
NM_000890
Chromosomal Location
11q24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Ion Channels: Potassium, Transmembrane
Molecular Weight
47.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KCNJ5
Species
Human
Protein ID
NP_000881
Overview
Recombinant protein of human potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3762
Uniprot URL
https://www.uniprot.org/uniprot/P48544
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000890
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000881
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