KCNJ5 (NM_000890) Human Recombinant Protein

Product Specifications

Background

This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas. [provided by RefSeq, Aug 2017]

Overview

Recombinant protein of human potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5)

Synonyms

CIR; GIRK4; KATP1; KIR3.4; LQT13

Gene ID

3762

UniProt

P48544, A0A5J6E2W8

Accession Number mRNA

NM_000890

Chromosomal Location

11q24.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Ion Channels: Potassium, Transmembrane

Molecular Weight

47.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.