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Aurora B (AURKB) (NM_004217) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Overview

Recombinant protein of human aurora kinase B (AURKB)

Synonyms

AIK2; AIM-1; AIM1; ARK-2; ARK2; AurB; aurkb-sv1; aurkb-sv2; IPL1; PPP1R48; STK-1; STK5; STK12

Gene ID

9212

UniProt

Q96GD4

Accession Number mRNA

NM_004217

Chromosomal Location

17p13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase, Stem cell - Pluripotency

Molecular Weight

39.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

AURKB

Species

Human

Protein ID

NP_004208

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9212

Uniprot URL

https://www.uniprot.org/uniprot/Q96GD4

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004217

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004208

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