What is the catalog number for GNA11 (NM_002067) Human Recombinant Protein?

The catalog number for GNA11 (NM_002067) Human Recombinant Protein is PH37324M5.

What sizes are available for GNA11 (NM_002067) Human Recombinant Protein?

GNA11 (NM_002067) Human Recombinant Protein is available in the following size(s): 20 µg.

Is GNA11 (NM_002067) Human Recombinant Protein in stock?

GNA11 (NM_002067) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

GNA11 (NM_002067) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11) . Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2) . Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. [provided by RefSeq, Dec 2013]

Overview

Recombinant protein of human guanine nucleotide binding protein (G protein), alpha 11 (Gq class) (GNA11)

Synonyms

FBH; FBH2; FHH2; GNA-11; HHC2; HYPOC2

Gene ID

2767

UniProt

P29992

Accession Number mRNA

NM_002067

Chromosomal Location

19p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Calcium signaling pathway, Gap junction, GnRH signaling pathway, Long-term depression, Vascular smooth muscle contraction

Field of Research

Calcium signaling pathway, Gap junction, GnRH signaling pathway, Long-term depression, Vascular smooth muscle contraction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

41.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.