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Galactoside 2 alpha L fucosyltransferase 1 (FUT1) (NM_000148) Human Recombinant Protein

Selected Variant

PH37295M5

Size: 20 µg

Product Specifications

Background

This gene encodes a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the synthesis of soluble A and B antigens. This is one of two genes encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group. [provided by RefSeq, Aug 2016]

Overview

Recombinant protein of human fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) (FUT1)

Synonyms

H; HH; HSC

Gene ID

2523

UniProt

P19526, Q6IZA2

Accession Number mRNA

NM_000148

Chromosomal Location

19q13.33

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways

Field of Research

Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

41.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FUT1

Species

Human

Protein ID

NP_000139

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2523

Uniprot URL

https://www.uniprot.org/uniprot/P19526

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000148

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000139

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