Myostatin Propeptide (MSTN) (NM_005259) Human Recombinant Protein
Product Specifications
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
Synonyms
GDF8; MSLHP
Gene ID
2660
UniProt
O14793, Q53S46
Accession Number mRNA
NM_005259
Chromosomal Location
2q32.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
42.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MSTN
Species
Human
Protein ID
NP_005250
Overview
Recombinant protein of human myostatin (MSTN)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2660
Uniprot URL
https://www.uniprot.org/uniprot/O14793
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005259
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005250
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