Proteinase Activated Receptor 4 (F2RL3) (NM_003950) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016]
Synonyms
PAR4
Gene ID
9002
UniProt
Q96RI0
Accession Number mRNA
NM_003950
Chromosomal Location
19p13.11
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Neuroactive ligand-receptor interaction
Field of Research
Neuroactive ligand-receptor interaction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, GPCR, Transmembrane
Molecular Weight
36.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
F2RL3
Species
Human
Protein ID
NP_003941
Overview
Recombinant protein of human coagulation factor II (thrombin) receptor-like 3 (F2RL3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9002
Uniprot URL
https://www.uniprot.org/uniprot/Q96RI0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003950
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003941
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