CD226 (NM_006566) Human Recombinant Protein
Product Specifications
Background
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Synonyms
DNAM-1; DNAM1; PTA1; TLiSA1
Gene ID
10666
UniProt
Q15762
Accession Number mRNA
NM_006566
Chromosomal Location
18q22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cell adhesion molecules (CAMs)
Field of Research
Cell adhesion molecules (CAMs)
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
36.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CD226
Species
Human
Protein ID
NP_006557
Overview
Recombinant protein of human CD226 molecule (CD226)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10666
Uniprot URL
https://www.uniprot.org/uniprot/Q15762
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006566
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006557
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