SPTSSB (NM_001040100) Human Recombinant Protein
Product Specifications
Background
Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTB is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]) .[supplied by OMIM, Nov 2010]
Synonyms
ADMP; C3orf57; SSSPTB
Gene ID
165679
UniProt
Q8NFR3, Q6ZWB5
Accession Number mRNA
NM_001040100
Chromosomal Location
3q26.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SPTSSB
Species
Human
Protein ID
NP_001035189
Overview
Recombinant protein of human chromosome 3 open reading frame 57 (C3orf57)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/165679
Uniprot URL
https://www.uniprot.org/uniprot/Q8NFR3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001040100
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001035189
Curated Selection
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