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CAPZB (NM_004930) Human Recombinant Protein

Selected Variant

PH37255M5

Size: 20 µg

Product Specifications

Background

This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. A pseudogene of this gene is located on the long arm of chromosome 2. Multiple alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, Aug 2013]

Overview

Recombinant protein of human capping protein (actin filament) muscle Z-line, beta (CAPZB)

Synonyms

CAPB; CAPPB; CAPZ

Gene ID

832

UniProt

P47756, A0A384MR50, Q7L4N0

Accession Number mRNA

NM_004930

Chromosomal Location

1p36.13

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

30.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CAPZB

Species

Human

Protein ID

NP_004921

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/832

Uniprot URL

https://www.uniprot.org/uniprot/P47756

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004930

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004921

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