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FBXO2 (NM_012168) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. [provided by RefSeq, Jul 2008]

Synonyms

FBG1; Fbs1; FBX2; NFB42; OCP1

Gene ID

26232

UniProt

Q9UK22

Accession Number mRNA

NM_012168

Chromosomal Location

1p36.22

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Ubiquitin mediated proteolysis

Field of Research

Ubiquitin mediated proteolysis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

33.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FBXO2

Species

Human

Protein ID

NP_036300

Overview

Recombinant protein of human F-box protein 2 (FBXO2)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/26232

Uniprot URL

https://www.uniprot.org/uniprot/Q9UK22

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_012168

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_036300

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