FBXO2 (NM_012168) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. [provided by RefSeq, Jul 2008]
Synonyms
FBG1; Fbs1; FBX2; NFB42; OCP1
Gene ID
26232
UniProt
Q9UK22
Accession Number mRNA
NM_012168
Chromosomal Location
1p36.22
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
33.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FBXO2
Species
Human
Protein ID
NP_036300
Overview
Recombinant protein of human F-box protein 2 (FBXO2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/26232
Uniprot URL
https://www.uniprot.org/uniprot/Q9UK22
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012168
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036300
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