Acyl coenzyme A Thioesterase 4 (ACOT4) (NM_152331) Human Recombinant Protein
Product Specifications
Background
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:16940157) . ACOT4 is a peroxisomal succinyl-coenzyme A thioesterase can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs (PubMed:16940157) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human acyl-CoA thioesterase 4 (ACOT4)
Synonyms
PTE-Ib; PTE1B; PTE2B
Gene ID
122970
UniProt
Q8N9L9
Accession Number mRNA
NM_152331
Chromosomal Location
14q24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Biosynthesis of unsaturated fatty acids
Field of Research
Biosynthesis of unsaturated fatty acids
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
46.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ACOT4
Species
Human
Protein ID
NP_689544
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/122970
Uniprot URL
https://www.uniprot.org/uniprot/Q8N9L9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_152331
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_689544
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