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USP21 (NM_012475) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

Overview

Recombinant protein of human ubiquitin specific peptidase 21 (USP21), transcript variant 1

Synonyms

USP16; USP23

Gene ID

27005

UniProt

Q9UK80

Accession Number mRNA

NM_012475

Chromosomal Location

1q23.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protease

Molecular Weight

62.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

USP21

Species

Human

Protein ID

NP_036607

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/27005

Uniprot URL

https://www.uniprot.org/uniprot/Q9UK80

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_012475

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_036607

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