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SNRPE (NM_003094) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a core component of U small nuclear ribonucleoproteins, which are key components of the pre-mRNA processing spliceosome. The encoded protein plays a role in the 3' end processing of histone transcripts. This protein is one of the targets in the autoimmune disease systemic lupus erythematosus, and mutations in this gene have been associated with hypotrichosis. Several pseudogenes of this gene have been identified. [provided by RefSeq, Jun 2016]

Overview

Recombinant protein of human small nuclear ribonucleoprotein polypeptide E (SNRPE)

Synonyms

HYPT11; Sm-E; SME; snRNP-E

Gene ID

6635

UniProt

P62304

Accession Number mRNA

NM_003094

Chromosomal Location

1q32.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Spliceosome

Field of Research

Spliceosome

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Stem cell - Pluripotency

Molecular Weight

10.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SNRPE

Species

Human

Protein ID

NP_003085

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6635

Uniprot URL

https://www.uniprot.org/uniprot/P62304

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003094

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003085

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