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FKBP2 (NM_004470) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

Synonyms

FKBP-13; FKBP13; PPIase

Gene ID

2286

UniProt

P26885, Q53XJ5

Accession Number mRNA

NM_004470

Chromosomal Location

11q13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

13.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FKBP2

Species

Human

Protein ID

NP_004461

Overview

Recombinant protein of human FK506 binding protein 2, 13kDa (FKBP2), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2286

Uniprot URL

https://www.uniprot.org/uniprot/P26885

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004470

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004461

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