GFUS (NM_003313) Human Recombinant Protein

Product Specifications

Background

Tissue specific transplantation antigen P35B is a NADP (H) -binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human tissue specific transplantation antigen P35B (TSTA3)

Synonyms

FX; P35B; SDR4E1; TSTA3

Gene ID

7264

UniProt

Q13630, A0A140VKC8

Accession Number mRNA

NM_003313

Chromosomal Location

8q24.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways

Field of Research

Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

35.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GFUS

Species

Human

Protein ID

NP_003304

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7264

Uniprot URL

https://www.uniprot.org/uniprot/Q13630

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003313

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003304

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