ZWINT (NM_007057) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
HZwint-1; KNTC2AP; SIP30; ZWINT1
Gene ID
11130
UniProt
O95229
Accession Number mRNA
NM_007057
Chromosomal Location
10q21.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
31.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ZWINT
Species
Human
Protein ID
NP_008988
Overview
Recombinant protein of human ZW10 interactor (ZWINT), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11130
Uniprot URL
https://www.uniprot.org/uniprot/O95229
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007057
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_008988
Curated Selection
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