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ZWINT (NM_007057) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

HZwint-1; KNTC2AP; SIP30; ZWINT1

Gene ID

11130

UniProt

O95229

Accession Number mRNA

NM_007057

Chromosomal Location

10q21.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

31.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ZWINT

Species

Human

Protein ID

NP_008988

Overview

Recombinant protein of human ZW10 interactor (ZWINT), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/11130

Uniprot URL

https://www.uniprot.org/uniprot/O95229

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_007057

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_008988

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