TRPC3 (NM_003305) Human Recombinant Protein
Selected Variant
PH37098M5
Size: 20 µg
Product Specifications
Background
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Overview
Recombinant protein of human transient receptor potential cation channel, subfamily C, member 3 (TRPC3), transcript variant 2
Synonyms
SCA41; TRP3
Gene ID
7222
UniProt
Q13507
Accession Number mRNA
NM_003305
Chromosomal Location
4q27
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
Molecular Weight
97.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TRPC3
Species
Human
Protein ID
NP_003296
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7222
Uniprot URL
https://www.uniprot.org/uniprot/Q13507
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003305
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003296
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